In this module you will explore how cell, tissue and systems respond to cell death. These responses will include cell death, inflammation, neoplasia, hypertrophy, hyperplasia and how tissues respond to injury and repair.
You will be introduced to principles of epidemiology by defining
• key terms
• discussing the roles of local, national and international public health organisations in the surveillance of disease and screening programmes
• recording and evaluating epidemiological data

You will explore the significance and impact of epidemiology and Public Health by reference to Health Protection, disease control, emergency planning, planning provision of health services, introduction of strategies to improve health and targeting at risk groups.

Your knowledge of genomics (introduced in other modules) will be developed to focus on aspects of genome-based personal healthcare such as drug dosage based on CYP profile, and targeted cancer treatments such as Herceptin and Imatinib.

You will discuss the sociology of health and illness by considering the diversity of patients referred to HCS services (e.g. age, culture, ethnicity, spiritual and religious beliefs, disabilities). Your discussions will include the role of self-care, life-threatening illness and the patient involvement decision about their healthcare.

You will be introduced to clinical bioinformatics and health informatics with an overview of the range of information systems, applications and management. You will also consider governance and ethical frameworks and the impact of these systems on the patients.

Ahmed,N., Dawson,M., Smith,C., Wood,E. (2006). Biology of Disease. Gartland Science.
Ahmed,N., Glencross, H., Wang, Q.(2016). Biomedical Science in Practice. OUP.

1. Describe how biological cells, tissues and systems respond to disease.
Knowledge and Understanding

2. Explain the principles and core concepts of clinical genetics, genomics and personalised/precision medicine and discuss these in the context of patients referred to HCS services
Knowledge and Understanding

3. Explain the basis of epidemiology, public health, health prevention and health protection and discuss these in relation to the role of the public health function and HCS services.
Analysis
Problem Solving

4. Discuss the principles and core concepts of the sociology of health and illness and discuss those relevant to patients typically referred to HCS services.
Enquiry

5. Explain the principles of clinical bioinformatics and health informatics and discuss their impact on health care, health and HCS services
Application

The module is delivered as a blend of DL and face-to-face.

Face to face contac will allow you to consolidate the material covered and demonstrate your knowledge and understanding of the material covered.

Independent and Distance Learning Study Hours together with practice-based workshops/practical work. Reading PowerPoint presentations
and completing on-line tutor led activity, as well as literature search/reading/ preparation for practicals and supplementing lecture materia. You will also write up practical reports and workshop materia and prepare for assessment.

Students will be required to complete 2 pieces of summative assessment

1. One portfolio (total approx1500 words) of short reports based on the workshop sessions. There will be 4 components – students will only receive one final mark for the portfolio which will be a combination of the marks for each portfolio component. (Learning outcomes 3 and 4) Weighting 10% for each component (40% total)
2. The final assessment to be taken, 1 - hour class test (Learning outcomes 1, 2 and 5) Weighting 60%

Additional Assessment Details (including formative feedback / assessment):

You will be provided with formative assessment and feedback via the inclusion of in-class exercises and discussions.