In this module you will develop knowledge and understanding of the chemical principles, structures and processes which underpin life in all its forms.

Chemical principles will encompass bonding, valency, the concept of pH and thermodynamics. Structures will begin at the basic level (simple units) and develop to complex with respect to molecules; for all molecules functional groups for example hydroxyl, amine, and thiol will be introduced, proteins will begin with amino acids and cover the levels of structure to tertiary and quaternary with examples of different types inclusive of enzymes, antibodies and structural proteins, nucleic acids will begin with bases through to the polymers of DNA and RNA (different forms), carbohydrates will begin with the monosaccharides through to polysaccharides with examples such as glycogen and cellulose and specialised monosaccharides attached to proteins and lipids, lipids will begin with the range of fatty acids and their modification to more complex glycerides and examples of steroids. The way that these molecules are organised to create organelles and cells (prokaryotic and eukaryotic) and viruses will be the final structures you study.
Processes will relate structure to function of each of the major classes of molecule, inclusive in this will be the role and action of enzymes . You will also be introduced to the processes of synthesis of complex molecules, (proteins, nucleic acids and lipids) which will include transcription and translation and energy transformation; focusing on the formation of adenosine triphosphate (ATP) via phosphorylated and cellular respiration

Essential: Brown, T. A. (2017) Biochemistry, Banbury: Scion Publishing
Web resource (online Biology book): https://cnx.org/contents/GFy_h8cu@10.118:fVAf83sY@13/Preface

Recommended:
Reed, R., Weyers, J. and Jones, A. (2016) Practical Skills in Biology, 6th ed., Harlow, Pearson
Campbell, N.A., Reece, J. B., Urry, L., Cain, M.L., Wasserman, S.A., Minorsky, P.V. and Jackson, R.B. (2014) Biology: A Global Approach 10th ed., Harlow: Pearson
Fry, M. and Page E. (2012) Catch UP Chemistry 2nd ed., Banbury: Scion Publishing
Bradley, P. and Calvert, J. (2013) Catch Up Biology 2nd ed., Banbury: Scion Publishing
Nelson, D. L. and Cox, M. M. Lehninger (2013) Principles of Biochemistry 6th ed., New York: WH Freeman.

Equipped lecture room and equipped laboratory (access to interactive technology in all teaching rooms)
Internet access
Blackboard VLE
Library

1. Demonstrate knowledge of fundamental chemical principles and chemical structures and processes that form the basis of life up.
Knowledge and Understanding

2. Demonstrate knowledge of complex chemical structures and processes that form the basis of life up to the cell (inclusive of prokaryote and eukaryote cell structure and virus structure).
Knowledge and Understanding

3. Safely and competently undertake practical investigations and develop new laboratory skills to demonstrate the properties of biochemical molecules or biochemical and cellular processes and evaluate the outcomes.
Enquiry
Application

1. A portfolio of competencies: demonstration of knowledge of health and safety, basic laboratory skills – (This element needs to be passed) weighted at 10% (learning outcomes 3)

2. A portfolio of practical reports (500 words each) from 4 specified sessions within the module (2 per semester) – weighting 30 % (learning outcome 3)

3. A 1 hour exam at the end of semester 1 – weighted at 30% (learning outcomes 1 & 3)

4. A 1 hour exam at the end of semester 2 – weighted at 30 % (learning outcomes 2 & 3)
[FINAL]

Formative feedback/assessment will occur via self and peer assessed feedback whilst working through practicals and workshops and for practice exam questions. In addition feedback on completion of competency checks will provide formative input.

The Contact sessions of this module will comprise of Lectures, practicals and workshops including group presentations, discussions/student led discussions and quizzes.

Independent study hours: 105
Preparation for lectures/workshops and practicals - 100 hours

In this module you will develop knowledge and understanding of the chemical principles, structures and processes which underpin life in all its forms.

Chemical principles will encompass bonding, valency, the concept of pH and thermodynamics. Structures will begin at the basic level (simple units) and develop to complex with respect to molecules; for all molecules functional groups for example hydroxyl, amine, and thiol will be introduced, proteins will begin with amino acids and cover the levels of structure to tertiary and quaternary with examples of different types inclusive of enzymes, antibodies and structural proteins, nucleic acids will begin with bases through to the polymers of DNA and RNA (different forms), carbohydrates will begin with the monosaccharides through to polysaccharides with examples such as glycogen and cellulose and specialised monosaccharides attached to proteins and lipids, lipids will begin with the range of fatty acids and their modification to more complex glycerides and examples of steroids. The way that these molecules are organised to create organelles and cells (prokaryotic and eukaryotic) and viruses will be the final structures you study.
Processes will relate structure to function of each of the major classes of molecule, inclusive in this will be the role and action of enzymes . You will also be introduced to the processes of synthesis of complex molecules, (proteins, nucleic acids and lipids) which will include transcription and translation and energy transformation; focusing on the formation of adenosine triphosphate (ATP) via phosphorylated and cellular respiration