Greenwood, D., Slack, R.C. and Peutherer, J.F. (2002) Medical Microbiology (16th Ed.) Churchill Livingstone
Henderson, B., Wilson, M., McNab, R. and Lax, A.J. (1999) Cellular Microbiology:Bacteria-Host Interactions in Health and Disease. Wiley
Roberts, L.S. and Janovy, J. (1996). Foundation of Parasitology (5th Edition). Wm. C. Brown.

Level 1 Cell Biology or Disease

Lecture theatre, networked computers to access web based material, appropriate texts in library.

Material will be delivered by twelve, two-hour tutor led lectures. The lecture programme will highlight the major themes within the module.
Lecture material will be reinforced by a series of student centred tasks involving various texts, reviews and material available electronically.

Students will be required to complete two pieces of summative assessment.
1. Two-hour examination. Students answer three from five questions. Weighting ? 70%. Outcomes 1 and 3
2. Public Information Leaflet on specified infectious agent. Weighting 30%. Outcome 2.

Students will be provided with formative assessment and feedback via
Revision session looking at typical exam questions. A series of work sheets directing students to additional background material, summarising points and comparing and contrasting specific material.

The principles of pathogenicity introduced in Level 1 will be developed by an in-depth consideration of the factors that make organisms pathogens. This will include the infectious dose, adhesion, growth of the pathogen in the host and how pathogens exert damage in the host. Interactions between the host and infectious agent will be discussed, in particular the host?s immune response how the host tries to eliminate pathogens and how infectious agents successfully evade the host immune system. The principles of epidemiology will be investigated including the problems and factors affecting nosocomial infections. The importance of humans and animals as reservoirs will be discussed as well as the importance and variation of transmission of the pathogen from the reservoir to a susceptible host. Public health measures used to try to control infectious diseases will be critically appraised. Illustrative examples will be used throughout the module. Current/topical issues such as emerging and re-emerging infectious diseases, and public concern about vaccines will be debated. Examples throughout will be taken from a range of pathogens (bacteria, protozoa, fungi viruses and other infectious agents) and may be influenced by pathogens topical at the time of delivery.