1. On completion of this module you will be able to explain how dysfunction of normal processes can contribute to the development of disease.
Communication, Reflection

2. On completion of this module you will be able to explain the role of the clinical laboratory specialties as well as being able to apply an integrated approach in the investigation of pathological disease.
Problem solving, Enquiry, Application

3. On completion of this module you will be able to describe the variety of sample types and collection methods available to investigate disease. You will be able to explain how these samples are analysed within specific disciplines as well as being able to discuss the information that can be obtained from them.
Knowledge and Understanding, Learning, Analysis

A minimum of 40% in BOTH summative assessments is required to pass the module.

Assessment 1: In-class tests. A series of short tests designed to evaluate understanding of lecture sessions and further reading, as well as the analysis of laboratory data and experimental techniques (50 %) (LO 3)

Assessment 2: Practical Case-based Discussion. A viva-style discussion based on a final practical case simulation. This is the FINAL assessment. (50 %) (LOs 1 and 2)

In this module you will investigate the processes that contribute to our overall health and wellbeing before considering how changes to, or dysfunction of, these processes can contribute to disease. Consideration will be given to the collection of diagnostic samples as well as the types of samples collected. This will include investigation of neoplastic disease (cellular pathology), pathogenic and non-pathogenic microorganisms (medical microbiology), haematological function and dysfunction (haematology), haemostasis in health and disease (coagulation), reproductive function and dysfunction (clinical embryology), immunological function and dysfunction (clinical immunology), biochemical and metabolic dysfunction (clinical biochemistry) as well as infectious disease and substance abuse. Consideration of the application of clinical genetics will be given across all fields and this will include aspects of medical ethics.

You will consider the application of current techniques within each area, as well as technological advances that allow disease to be diagnosed, or predicted, in both times of apparent good health and disease. This will include consideration of cellular, biochemical, and molecular investigations.

Organised activities will provide a means of support where you will be able to reflect upon your development, feedback and progression within your studies. These activities may be conducted online or face-to-face. The module comprises predominantly small group workshop activity (which may be undertaken using software such as Microsoft Teams or Blackboard Collaborate), such as problem based or student centred enquiry-led learning together with key lectures and seminars providing the backbone of study. Data science and other related skills will draw upon your work in other core modules and may include presentation in different formats and interpersonal communication skills development.¿¿ The detailed schedule is published on the blackboard course pages at the start of the module and in the Module Handbook.¿

Practical skills in Biomolecular Sciences 5th Ed. Reed, R., Weyers, J and Jones, A.¿ (2016)

The IBMS Fundamentals series will be used throughout to support discussions.
https://global.oup.com/academic/content/series/f/fundamentals-of-biomedical-science-ibms/?cc=gb&lang=en&

Reference to primary literature will be strongly encouraged.

Bioscience laboratories with equipment and consumables. Assistance of technical skills specialists where appropriate.¿¿

You will investigate the processes that contribute to our overall health and wellbeing before considering how changes to, or dysfunction of, these processes can contribute to disease. Consideration will be given to the collection of diagnostic samples as well as the types of samples collected. This will include investigation of neoplastic disease (cellular pathology), pathogenic and non-pathogenic microorganisms (medical microbiology), haematological function and dysfunction (haematology), haemostasis in health and disease (coagulation), reproductive function and dysfunction (clinical embryology), immunological function and dysfunction (clinical immunology), biochemical and metabolic dysfunction (clinical biochemistry) as well as infectious disease and substance abuse. Consideration of the application of clinical genetics will be given across all fields and this will include aspects of medical ethics.

You will consider the application of current techniques within each area, as well as technological advances that allow disease to be diagnosed, or predicted, in both times of apparent good health and disease. This will include consideration of cellular, biochemical, and molecular investigations.