Throughout this module you will develop knowledge and understanding of how dysfunction of the core anatomical, physiological, cellular, and biochemical processes can contribute to the development of human disease. Using specific examples from; neoplastic disease (cellular pathology), pathogenic microorganisms (medical microbiology), haematological dysfunction (haematology), haemostasis (coagulation), reproductive dysfunction (clinical embryology), immunological dysfunction (clinical immunology), and biochemical and metabolic dysfunction (clinical biochemistry), we will investigate the consequences of dysfunction with a specific focus on the inter-relationship between systems. In addition, we will also consider how extremes of age and lifestyle choices can influence disease susceptibility and progression.

This module is mapped against the Quality Assurance Agency Benchmark for Biomedical Science and the National School of Healthcare Science Practitioner Training Programme curriculum and contributes to the Healthcare Science Practitioner Degree Apprenticeship Standard by developing your knowledge of the underlying scientific principles of the investigations offered by healthcare science services.

A minimum of 40% in BOTH summative assessments is required to pass the module.

Essay – LO 2
You will author a 1500-word essay that allows you to demonstrate competence in learning outcome 2. You will have an opportunity to personalise your learning through the choice of examples used throughout the essay.

Class Test – LOs 1,3
The class test will utilise short answer questions, that will cover the breadth and depth of topics that are covered throughout the module and will specifically address learning outcomes 1 and 3.

This module is delivered as a blend of asynchronous online learning sessions, on campus study days and work-based study. Within each learning unit you will be given a range of learning outcomes and directed through a variety of learning material (for example recorded lectures, online exercises or collaborative activities) to work though asynchronously together with an opportunity to check and develop your learning (for example through online quizzes, challenge questions or discussion fora). You are encouraged to reflect upon the academic content of the module and consider how this is applicable within your workplace.

Your learning is supported by a group discussion board and weekly online sessions where you can discuss your learning with the academic teaching team.

Explain how dysfunction of anatomical, physiological, cellular, and biochemical processes can contribute to the development of disease.

Knowledge and Understanding

Learning

Critically analyse the consequences of dysfunction with a specific focus on the inter-relationships between the individual systems.

Knowledge and Understanding

Analysis

Problem-solving

Application

Reflection

Describe a range of pathogenic organisms and their associated pathogenic mechanisms and illustrate the consequences of these diseases on normal anatomical, physiological, cellular, and biochemical processes.

Knowledge and Understanding

Learning

Problem-solving

Application

You will require access to a computer with internet access.
Access to specialist facilities on campus.

The IBMS Fundamentals series will be used throughout to support discussions.
https://global.oup.com/academic/content/series/f/fundamentals-of-biomedical-science-ibms/?cc=gb&lang=en&

Reference to primary literature will be strongly encouraged.

Throughout this module you will develop knowledge and understanding of how dysfunction of the core anatomical, physiological, cellular, and biochemical processes can contribute to the development of human disease. Using specific examples we will investigate the consequences of dysfunction with a specific focus on the inter-relationship between systems. In addition, we will also consider how extremes of age and lifestyle choices can influence disease susceptibility and progression.