1. critically evaluate current knowledge on genetic, environmental and behavioural factors that precipitate the development of a human diseased state.
Communication
Analysis

2. critically evaluate how understanding of the aetiology of a disease develops new methods of diagnosis and treatments.
Knowledge and Understanding
Analysis

The module studies the interrelationships that are involved in the development of multifactorial human diseases and of their relationships with each other. Many of the major chronic multifactorial disorders that affect the World’s population in the 21st Century are a result of genetic, environmental or even it could be argued behavioural factors. This module explores the impact of these factors on disease development and thus reviews the current understanding of their aetiology, pathogenesis, diagnosis and treatment. Examples of diseases are cardiovascular disease (such as atherosclerosis and high blood pressure), diabetes mellitus, obesity and amyloidosis.

Many of the major chronic non-communicable diseases that affect the World’s population in the 21st Century are a result of epigenetic, environmental and behavioural factors. This module explores the interrelationship of these factors and how they contribute to disease development. It reviews our current understanding of the causes of disease, pathogenesis, diagnosis and treatment.

Lectures will focus on key aspects relating to the subject area that are fundamental to further independent study. Lectures will also include the opportunity to discuss recent research papers and articles relevant to the diseases discussed. Contact time will also be used to direct formative tasks to guide independent study and to prepare for module assessments.

Relevant journal articles obtained via the library or free journal access.

D. L. Nelson & M. M. Cox (2017) Lehninger Principles of Biochemistry, International Edition, 7th edition. Macmillan Learning

Halliwell B & Gutteridge J. M. C. (2015) Free Radicals in Biology and Medicine 7th edition. Oxford University Press

Lecture room
Internet linked PC
Library – and access to e-journals and e-books

1. An article in the style and format of that found in the New Scientist. Using specific named examples to describe and explain the aetiology of multi-factorial diseases and the impact the understanding of these diseases is having on diagnosis and treatment. LO1 and LO2 100 % 3500 words