Molecular Biology of the Cell 4th ed (2002) Alberts B. et al, Garland Science
ISBN: 0-8153-4072-9
An array of electronic media/links will also be provided

Course textbooks and learning materials - as supplied
Suitable computer that is able to access the WWW, the University server and load/run Blackboard.
Library facilities as necessary
This module will be delivered via internet

The module makes use of Blackboard as the VLE. Activities will be posted on the module on a weekly basis. Each activity will contain background notes, information and a task associated with the topic . A core text will be used for further reading around the basic principles and learners will be directed to further reading through citations or directly through a network link. You will need to spend approximately 15h per week study time, this may vary depending on your previous knowledge and the depth of study required for each activity. Part of the 15h time allocated will be dedicated for answering on-line formative assessments and for taking part in chat rooms.

The module will consider the molecular basis of chronic diseases that arise as a consequence of one or more contributory factors i.e. inherited, environmental or behavioural factors. How each of these factors can give rise to a diseased state will be studied and then the consequences of these factors working together will be investigated to show disease progression. While following disease progression the consequence of changes occurring within the metabolism and physiology of an individual will be addressed. The module will begin by considering different factors leading to the development of non-infectious diseases, subsequently an introduction to the response of the immune system to the development of these diseases will be made. This is followed by the study of a range of diseases demonstrating the multifactorial nature and metabolic and physiological aberrations occurring during disease progression. Each stage will be supported by relevant tasks to enable an increase in knowledge and understanding within the area.

Formative: Each week a task associated with the topic to underpin the area covered will be set. Exercises may be set using the on-line quiz facility on Blackboard and discussion between students will be encouraged allowing peer and tutor feedback to be given.

Summative: A review on a non-infectious disease of their choice emphasising the multifactorial aspects and biochemical consequences incorporating an analysis of the current literature and understanding of the disease. (3,000 words) (1,2,3)
Topics suggested by students themselves will be encouraged although suggestions will be made as the course progresses.

PASS CRITERIA
Review shows coherence and relevance to the disease chosen. A good understanding of the subject is shown, there is evidence of reading beyond that recommended and good examples are incorporated. Task competently completed.

MERIT CRITERIA
Review shows a very good awareness of the subject matter. Review is lucid and material is cogent. Good quality is shown by use of sound reading and critical analysis of the available literature beyond that recommended using well focussed examples and arguments. All areas are addressed substantially.

DISTINCTION CRITERIA
Review shows originality and creativity in approach. Accurate and demonstrates a thorough understanding of the subject matter. The work is underpinned by a comprehensive review of the available literature beyond the recommendations of the course. Use of examples and critical analysis of the available information is excellent. Task is thoroughly and comprehensively completed