1. Review the current evidence that demonstrates many diseased states to be of a multifactorial origin
2. Critically evaluate published material relevant to the understanding of the molecular basis of the diseased state and to demonstrate scientific understanding and reasoning in the evaluation
3. Integrate material from a variety of different sources leading to the generation of a considered ad well-argued opinion

The module will consider the molecular basis of chronic diseases that arise as a consequence of one or more contributory factors i.e. inherited, environmental or behavioural factors. How each of these factors can give rise to a diseased state will be studied and then the consequences of these factors working together will be investigated to show disease progression. While following disease progression the consequence of changes occurring within the metabolism and physiology of an individual will be addressed. The module will begin by considering different factors leading to the development of non-infectious diseases, subsequently an introduction to the response of the immune system to the development of these diseases will be made. This is followed by the study of a range of diseases demonstrating the multifactorial nature and metabolic and physiological aberrations occurring during disease progression. Each stage will be supported by relevant tasks to enable an increase in knowledge and understanding within the area.

Chronic diseases occur as a consequence of one or more contributory factors. How these factors can lead to disease onset, progression and a disruption to normal metabolic and physiological processes will be addressed.

The Masters in Molecular Biology is delivered on campus through a combination of lectures workshops and practical classes alongside directed self-study. For this module, each week a workshop task associated with the topic to underpin the area covered will be set. Exercises may include quizzes facility and peer-to-peer discussions.

Alberts, B., Johnson, A, Lewis, J., Morgan, D., Raff, M., Roberts, K and Walter, P. (2014) Molecular Biology of the Cell 6th edition, Garland Science

An array of electronic media/links including links to relevant primary material will also be provided.

You will need access to a computer with access to the internet.

Formative feedback will be given over the tasks associated with the module topics. Discussion between students will be encouraged allowing peer and tutor feedback to be given.¿

Summative:- Coursework 100% distributed as follows:¿



Summative: A review on a non-infectious disease of their choice emphasising the multifactorial aspects and biochemical consequences incorporating an analysis of the current literature and understanding of the disease. (3,000 words) (1,2,3)
Topics suggested by students themselves will be encouraged although suggestions will be made